翻訳と辞書
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・ CX 46 Radio América
・ CX 58 Radio Clarín
・ CX 6 SODRE
・ CX 8 Radio Sarandí
・ CX Navarro
・ CX-5
・ CX-516
・ CX-546
・ CX157
・ CX3CL1
・ CX3CR1
・ Cx4
・ CX614
・ CX717
・ CXAM radar
CXC chemokine receptors
・ CXCL1
・ CXCL10
・ CXCL11
・ CXCL13
・ CXCL14
・ CXCL15
・ CXCL16
・ CXCL17
・ CXCL2
・ CXCL3
・ CXCL5
・ CXCL6
・ CXCL7
・ CXCL9


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CXC chemokine receptors : ウィキペディア英語版
CXC chemokine receptors


CXC chemokine receptors are integral membrane proteins that specifically bind and respond to cytokines of the CXC chemokine family. They represent one subfamily of chemokine receptors, a large family of G protein-linked receptors that are known as seven transmembrane (7-TM) proteins, since they span the cell membrane seven times. There are currently seven known CXC chemokine receptors in mammals, named CXCR1 through CXCR7.
==CXCR1 and CXCR2==
CXCR1 and CXCR2 are closely related receptors that recognize CXC chemokines that possess an E-L-R amino acid motif immediately adjacent to their CXC motif. CXCL8 (otherwise known as interleukin-8) and CXCL6 can both bind CXCR1 in humans, while all other ELR-positive chemokines, such as CXCL1 to CXCL7 bind only CXCR2.〔Tsai, H.-H., Frost, E., To, V., Robinson, S., ffrench-Constant, C., Geertman, R., Ransohoff, R.M., Miller, R.H. The chemokine receptor CXCR2 controls positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. Cell 110: 373-383, 2002.〕〔Pelus LM, Fukuda S. Peripheral blood stem cell mobilization: the CXCR2 ligand GRObeta rapidly mobilizes hematopoietic stem cells with enhanced engraftment properties. Exp Hematol. 2006 Aug;34(8):1010-20. PMID = 16863907〕 They are both expressed on the surface of neutrophils in mammals.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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